Peculiarities of vascularization of glioblastoma multiformis of brain hemisphere taken from the interventional neuroradiological methods in certain clinical cases

  • I S. Bobryk Volyn Regional Oinical Hospital
  • V.D. Rozumenko SO «Insitute of Neurosurgery named after acad. A.P. Romodanov of NAMS of Ukraine»
Keywords: glioblastoma multiformis, digital subtraction angiography, superselective cerebral angiography, vascular malformation, feeding-arteries, drain veins, tumor artheries, tumor veins.

Abstract

Objective – to show the effectiveness of digital subtraction angiography (DSA) and superselective angiography (SSCA) in patients with glioblastoma multiformis (GBM); to describe peculiarities of vascular architecture and hemodinamics of tumor in certain clinical cases.

Materials and methods. We selected 11 patients for the research with GBM of brain hemisphere. We performed DSA, computer tumography and magnetic resonance imaging in each case. In 4 cases we examined SSCA of tumor locus.

Results. Performing DSA in patients with GBM we obtained a certain information about vascular architecture and hemodinamics of tumor. High sensitivity of the method was shown for this type of pathology.

Conclusions. The information of DSA and SSCA in patients with GBM gives an opportunity to estimate the vascularity of the tumor. These methods may be recommend for using in this type of pathology.

Downloads

Download data is not yet available.

References

Bobryk I, Kukharuk V, Bobryk S, Fetsiak S, Chirko A, Hnativ R. Diagnostics and treatment of intracranial tumors with interventional neuroradiological methods (Ukr). Endovascular Neuroradiol (Ukr) [online]. 2015;11(1):30-40. Available at: http://www. endovasc-neuroradiology-journal.org.ua/wp-content/ uploads/PDF/11/04.pdf [Accessed 6 Mar. 2017].

Rumboldt Z. Brain imaging with MRI and CT. 1st ed. Cambridge: Cambridge University Press, 2012:330-1. ISBN 978-0-521-11944-3.

Su Y, Ali R, Feroze A, Li G, Lawton M, Choudhri O. Endovascular therapies for malignant gliomas: Challenges and the future. J. Clin. Neurosci [online]. 2016;26:26-32. Available at: http://wwwjocn-journal. com/article/S0967-5868(15)00569-X/abstract [Accessed 6 Mar. 2017]. doi: 10.1016/jjocn.2015.10.019.

Daumas-Duport C, Scheithauer B, O'Fallon J, Kelly P. Grading of astrocytomas: A simple and reproducible method. Cancer [online]. 1988;62(10):2152-65. Available at: http://onlinelibrary.wiley.com/doi/10.1002/1097- 0142(19881115)62:10 %3C2152::AID-CNCR28206210 15 %3E3.0.CO;2-T/pdf [Accessed 6 Mar. 2017]. do i:10.1002/10970142(19881115)62:10<2152::aidcn- cr2820621015>3.0.co;2-t.

Burkhardt J, Riina H, Shin B, Moliterno J, Hofstetter C, Boockvar J. Intra-arterial chemotherapy for malignant gliomas: A critical analysis. Intervent. Neuroradiol. [online]. 2011;17(3):286-95. Available at: http://journals. sagepub.com/doi/10.n77/159101991101700302 [Ac- cessed6 Mar. 2017]. doi: 10.1177/159101991101700302.

Johnson D, O’Neill B. Glioblastoma survival in the United States before and during the temozolomide era. J. Neuro-Oncol. 2011;107(2):359-64. doi 10.1007/ s11060-011-0749-4.

Nagy J, Chang S, Dvorak A, Dvorak H. Why are tumour blood vessels abnormal and why is it important to know? Br. J. Cancer [online]. 2009;100(6):865-9. Available at: http://www.nature.com/bjc/journal/v100/ n6/full/6604929a.html [Accessed 6 Mar. 2017]. doi: 10.1038/sj.bjc.6604929.

Nagy J, Dvorak A, Dvorak H. VEGF-A and the induction of pathological angiogenesis. Annual Review of Pathology: Mechanisms of Disease [online]. 2007;2(1):251- 75. Available at: http://www.annualreviews.org/ doi/full/ 10.1146/annurev.pathol.2.010506.134925 [Accessed 6 Mar. 2017]. doi: 10.1146/annurev. pathol.2.010506.134925.

Published
2017-03-01
How to Cite
Bobryk, I. S., & Rozumenko, V. (2017). Peculiarities of vascularization of glioblastoma multiformis of brain hemisphere taken from the interventional neuroradiological methods in certain clinical cases. Ukrainian Interventional Neuroradiology and Surgery, 19(1), 14-22. Retrieved from https://enj.org.ua/index.php/journal/article/view/40