Morphological characteristics of hypervascularized meningiomata: conjuncture and reality
Abstract
Objective – to describe of morphological assessment/characteristics of hypervascularized me- ningiomata after preliminary embolization of their vascular afferents.
Materials and methods. Samples of biological material (parts of meningiomata), taken from patients in conditions of neurosurgical operating room, served as the material for the study. Tumour fragments underwent standard histological tests (fixation in 12 % formaldehyde on phosphate-buffered saline, dehydration in ascending alcohol series and embedment in blocks). Histological sections were obtained with help of a rotary microtome (10-15 |im) and stained depending upon needs of the study (haematoxylin and eosin, Van Gieson and Brachet methods, sudan III-IV, Regaud’s iron hae- matoxylin). The results were evaluated under a LOMO light-optical microscope (* 100; 200; 400; 1350).
Results. The epithelial origin of meningiomata (arachnoidal endothelium) and typical localization of hypervascularized meningiomata (the growth source was concentrated along venous sinuses of the dura mater on the convex surface of the brain) contributed to formation of their own well-developed microcirculation system, therewith causing their structurally and functionally specific neogenesis (a clear order of cell distribution, appearance of marker components (verticillate structures, psammoma bodies, fibroblastic elements), neurofibromatosis II).
Conclusions. Results of the study revealed existence of several kinds of meningiomata – from typical forms to hypervascularized variants. Their epithelial origin (arachnoidal endothelium) and typical localization (the growth source was concentrated along venous sinuses of the dura mater on the convex surface of the brain) contributed to formation of their own well-developed microcirculation system, therewith causing their structurally and functionally specific neogenesis (a clear order of cell distribution, appearance of marker components (verticillate structures, psammoma bodies, fibroblastic elements), neurofibromatosis II).
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